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  • Factory Cheap Losartan Hydrochlorothiazide 100 Mg 25 Mg - Ledipasvir Actone /PVP  – CPF

    Factory Cheap Losartan Hydrochlorothiazide 100 Mg 25 Mg - Ledipasvir Actone /PVP – CPF

    雷迪帕韦丙酮/聚维酮 Ledipasvir actone/PVP 1256388-51-8 In-House     LPSM1   1256387-87-7 In-House     LPSM1-5   291775-59-2 In-House     LPSM2   1129634-44-1 In-House     LPS-6   1441670-89-8 In-House Ledipasvir acetone (GS-5885 acetone) is the active ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon. In Vitro Ledipasvir acetone is considered the active ingredient, which ...
  • Factory source Sofosbuvir Manufacturer - Doxycycline Monohydrate  – CPF

    Factory source Sofosbuvir Manufacturer - Doxycycline Monohydrate – CPF

    多西环素一水物 Doxycycline Monohydrate 17086-28-1 USP/EP Generic Name: doxycycline (DOX i SYE kleen) Brand Names: Acticlate, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Monodox, Morgidox, Oracea, Oraxyl, Periostat Targadox, Vibramycin calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs Dosage Form: capsule Doxycycline is a tetracycline antibiotic that fights bacteria in the body and  an antibiotic and broad-spectrum metalloproteinase (MMP) inhibi...
  • Factory directly Doxycycline Monohydrate 50 Mg - LOXO-101 1223403-58-4  – CPF

    Factory directly Doxycycline Monohydrate 50 Mg - LOXO-101 1223403-58-4 – CPF

    Background IC50: low nanomolar range for inhibition of all TRK family members LOXO-101 is a tropomyosin receptor kinases (TRK) inhibitor. The TRK family of neurotrophin receptors and their neurotrophin ligands regulate neuron growth, differentiation and survival. In vitro: In previous study, LOXO-101 was evaluated for off-target kinase enzyme inhibition against a panel of non-TRK kinases at a concentration of 1,000 nM and ATP concentrations around the Km. Results showed that LOXO-101 had grea...
  • 100% Original Factory Hydrochlorothiazide 50 - Agomelatine  – CPF

    100% Original Factory Hydrochlorothiazide 50 - Agomelatine – CPF

    Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu...
  • Good quality Daclatasvir - Lenalidomide  – CPF

    Good quality Daclatasvir - Lenalidomide – CPF

    Description Lenalidomide (CC-5013) is a derivative of Thalidomide and an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells. Background Lenalidomide ...
  • Excellent quality Use Of Rosuvastatin Calcium - Obeticholic Acid  – CPF

    Excellent quality Use Of Rosuvastatin Calcium - Obeticholic Acid – CPF

    Description Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy[1][2][3].   Background Obeticholic Acid (6alpha-ethyl-chenodeoxycholic acid, 6-ECDCA, INT-747) is a potent and selective agonist of FXR with EC50 value of 99 nM [1]. The farnesoid X receptor (FXR) is a nuclear bile acid receptor involved in bile acid homeostasis, liver ...
  • Factory Outlets Blood Pressure Medicine Hydrochlorothiazide - Doxycycline Hyclate  – CPF

    Factory Outlets Blood Pressure Medicine Hydrochlorothiazide - Doxycycline Hyclate – CPF

    Background Doxycycline hyclate is an antibiotic [1]. Doxycycline hyclate is a derivative of tetracycline and possesses the activities of anti-inflammatory and antimicrobial. Doxycycline inhibits dengue virus replication in vitro with a temperature-dependent manner. The IC50 value is 52.3μM at 37°C and 26.7μM at 40°C. It inhibits the dengue virus via inhibiting the NS2B-NS3 serine protease of the virus. 60μM doxycycline reduces the CPE of the DNEV2-infected cells [1]. Doxycycline is found to b...
  • Wholesale Pregabalin Supplier - Sacubitril Hemicalcium  – CPF

    Wholesale Pregabalin Supplier - Sacubitril Hemicalcium – CPF

        沙库比曲半钙盐 Sacubitril Hemicalcium 1369773-39-6 In-House     沙库比曲钠盐 149690-05-1 In-House     LCZ-4 1426129-50-1 In-House     LCZ-7 1012341-48-8 In-House     LCZ-8 1012341-50-2 In-House     LCZ-9 149690-12-0 In-House   Background AHU-377 hemicalcium salt is a hemicalcium salt form of AHU-377. It is an inhibitor of neprilysin with IC50 value of 5 nM [1]. AHU-377 and the angiotensin II AT1 receptor antagonist valsartan compose LCZ696 in a 1:1 molar rati...
  • Factory Cheap Hot Ticagrelor 90 Mg Uses - Doxycycline Monohydrate  – CPF

    Factory Cheap Hot Ticagrelor 90 Mg Uses - Doxycycline Monohydrate – CPF

    多西环素一水物 Doxycycline Monohydrate 17086-28-1 USP/EP Generic Name: doxycycline (DOX i SYE kleen) Brand Names: Acticlate, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Monodox, Morgidox, Oracea, Oraxyl, Periostat Targadox, Vibramycin calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs Dosage Form: capsule Doxycycline is a tetracycline antibiotic that fights bacteria in the body and  an antibiotic and broad-spectrum metalloproteinase (MMP) inhibi...
  • 18 Years Factory Canagliflozin Dosage - Ezetimibe  – CPF

    18 Years Factory Canagliflozin Dosage - Ezetimibe – CPF

    Background Ezetimibe is a potent and novel inhibitor of cholesterol absorption [1]. Cholesterol is a lipid molecule and is required to build and maintain membranes structural integrity and fluidity. Also, it serves as a precursor of vitamin D, bile acids and steroid hormones. In differentiated Caco-2 cells incubated with a carotenoid (1 μM), ezetimibe (10 mg/L) inhibited carotenoid transport with 50% inhibition for ɑ-carotene and β-carotene. Also, it inhibited the transport of β-cryptoxanthin...
  • PriceList for Pregabalin Effects - Pregabalin  – CPF

    PriceList for Pregabalin Effects - Pregabalin – CPF

    Pregabalin is not a GABAA or GABAB receptor agonist. Pregabalin is a gabapentinoid and acts by inhibiting certain calcium channels. Specifically it is a ligand of the auxiliary α2δ subunit site of certain voltage-dependent calcium channels (VDCCs), and thereby acts as an inhibitor of α2δ subunit-containing VDCCs. There are two drug-binding α2δ subunits, α2δ-1 and α2δ-2, and pregabalin shows similar affinity for (and hence lack of selectivity between) these two sites. Pregabalin is selective i...
  • China Wholesale Ticagrelor Factory - Enalapril Maleate  – CPF

    China Wholesale Ticagrelor Factory - Enalapril Maleate – CPF

    Background Enalapril Maleate Description Enalapril (maleate) (MK-421 (maleate)), the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor. In Vivo Enalapril (MK-421) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to enalaprilat following oral administration. Enalapril (MK-421) is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angio...