• Big Discount Rosuvastatin Calcium Generic - Folic Acid  – CPF

    Big Discount Rosuvastatin Calcium Generic - Folic Acid – CPF

    Background Extracted from Spinacia oleracea;Store the product in sealed, cool and dry condition Description Folic acid(Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. Clinical Trial NCT Number Sponsor Condition Start Date Phase NCT03332602 Swiss Federal Institute of Technology Iron-deficiency April 4, 2018 Not Applicable Storage 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, ...
  • Factory Outlets Blood Pressure Medicine Hydrochlorothiazide - Ticagrelor  – CPF

    Factory Outlets Blood Pressure Medicine Hydrochlorothiazide - Ticagrelor – CPF

    Background Ticagrelor is a novel antagonist of the P2Y12 receptor [1]. Ticagrelor has been reported to inhibit the prothrombotic effects of ADP on the platelet by against the P2Y12 receptor. Ticagrelor has shown the complete inhibition of platelet aggregation ex vivo. In addition Ticagrelor has suggested a dose-dependent inhibition of platelet aggregation in human being. Apart from these, Ticagrelor has also demonstrated an orally, actively, reversibly binding antagonist. Unlike other inhibit...
  • New Fashion Design for Doxycycline Hyclate 100mg Tablets - Pitavastatin Calcium  – CPF

    New Fashion Design for Doxycycline Hyclate 100mg Tablets - Pitavastatin Calcium – CPF

    匹伐他汀钙 Pitavastatin 147526-32-7 In-House     PI-5 3800-06-4 In-House     PI-6 145516-11-4 In-House     PI-7 121660-11-5 In-House   Description Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (L...
  • China Supplier Sugammadex Sodium - Niraparib 1038915-60-4  – CPF

    China Supplier Sugammadex Sodium - Niraparib 1038915-60-4 – CPF

    Description Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.   In Vitro Niraparib (MK-4827) inhibits PARP activity with EC50=4 nM and EC90=45 nM in a whole cell assay. MK-4827 inhibits proliferation of cancer cells with mutant BRCA-1 and BRCA-2 with CC50 in the 10-100 nM range. MK-4827 displays exce...
  • 8 Year Exporter Doxycycline Monohydrate 100mg For Sinus Infection - Lenalidomide  – CPF

    8 Year Exporter Doxycycline Monohydrate 100mg For Sinus Infection - Lenalidomide – CPF

    Description Lenalidomide (CC-5013) is a derivative of Thalidomide and an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells. Background Lenalidomide ...
  • Hot sale Doxycycline Hyclate 100mg For Ear Infection - Agomelatine  – CPF

    Hot sale Doxycycline Hyclate 100mg For Ear Infection - Agomelatine – CPF

    Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu...
  • One of Hottest for Doxycycline Hyclate For Bv - Sugammadex Sodium  – CPF

    One of Hottest for Doxycycline Hyclate For Bv - Sugammadex Sodium – CPF

    舒更葡糖钠 Sugammadex Sodium 343306-79-6 In-House Description Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a new reversal agent for neuromuscular block. Generic Name: sugammadex (soo GAM ma dex) Brand Name: Bridion Sugammadex reverses the effects of certain medications that are given during surgical procedures to relax your muscles. Sugammadex is used at the end of surgery, to help restore muscle function that has been blocked during surgery by the other ...
  • OEM manufacturer Doxycycline Monohydrate For Pneumonia - LCZ696(Sacubitril + Valsartan)  – CPF

    OEM manufacturer Doxycycline Monohydrate For Pneumonia - LCZ696(Sacubitril + Valsartan) – CPF

    Description LCZ696 (Sacubitril/Valsartan), comprised Valsartan (an ARB) and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure[1][2][3]. LCZ696 ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis.   Background LCZ696 is a first in class ARNi (angiotensin receptor neprilysin inhibitor) comprising anionic moieties of AR...
  • Reasonable price Doxycycline Mono For Acne - Tofacitnib Citrate  – CPF

    Reasonable price Doxycycline Mono For Acne - Tofacitnib Citrate – CPF

    Background Tofacitinib citrate, also known as CP-690550 citrate, is a potent inhibitor of janus kinase 3 (JAK3), a hematopoetic cell-restricted tyrosine kinase involved in signal transduction regulating lymphocyte survival, proliferation, differentiation, and apoptosis.  The inhibition is JAK3 specific with a selectivity 1000-fold more than other non-JAK family kinases. Besides inhibiting JAKS (IC50 = 1 nM), tofacitinib citrate also inhibits janus kinase 2 (JAK2) and janus kinase 1 (JAK1) wit...
  • 2020 Good Quality Velpatasvir Supplier - Agomelatine  – CPF

    2020 Good Quality Velpatasvir Supplier - Agomelatine – CPF

    Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu...
  • Special Price for Doxycycline Hyclate Oral - Sacubitril Hemicalcium  – CPF

    Special Price for Doxycycline Hyclate Oral - Sacubitril Hemicalcium – CPF

        沙库比曲半钙盐 Sacubitril Hemicalcium 1369773-39-6 In-House     沙库比曲钠盐 149690-05-1 In-House     LCZ-4 1426129-50-1 In-House     LCZ-7 1012341-48-8 In-House     LCZ-8 1012341-50-2 In-House     LCZ-9 149690-12-0 In-House   Background AHU-377 hemicalcium salt is a hemicalcium salt form of AHU-377. It is an inhibitor of neprilysin with IC50 value of 5 nM [1]. AHU-377 and the angiotensin II AT1 receptor antagonist valsartan compose LCZ696 in a 1:1 molar rati...
  • OEM/ODM Factory Medication Doxycycline Hyclate - Rivaroxaban  – CPF

    OEM/ODM Factory Medication Doxycycline Hyclate - Rivaroxaban – CPF

    Background Rivaroxaban, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide, is a potent small-molecule inhibitor of factor Xa which is a coagulation factor at a critical juncture in the blood coagulation pathway resulting in the generation of thrombin and the formation of clot. Rivaroxaban binds to the Tyr288 in S1 pocket of factor Xa through the interaction of Tyr288 and the chlorine substituent of the chlorothiophene moiety. The inhi...