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  • Icotrokinra hydrochloride

    Icotrokinra hydrochloride

    API’s Name CAS No. US DMF Patent Expiry Date (US) Current Status 
    Icotrokinra hydrochloride 3049491-48-4

     

    [Indication] 

    • Moderate-to-severe plaque psoriasis: For the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age and older weighing at least 40 kg who are candidates for systemic therapy or phototherapy.
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  • Iptacopan

    Iptacopan

    API’s Name CAS No. US DMF EU DMF Patent Expiry Date (US) Current Status 
    Iptacopan hydrochloride 1646321-63-2  2027.Q1   Jul.14, 2034
    Iptacopan hydrochloride monohydrate 2447007-60-3  2027.Q1 May, 2041

     

    [Indication] 

    • Paroxysmal nocturnal hemoglobinuria (PNH)：For the treatment of PNH in adult patients.
    • C3 glomerulopathy (C3G)：For the treatment of C3G in adult patients to reduce proteinuria.
    • Immunoglobulin A nephropathy (IgAN)：For the treatment of primary IgAN in adult patients with rapid progression risk to reduce proteinuria levels.
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