Hydrochlorothiazide Uses

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  • China Supplier Sugammadex Sodium - Niraparib 1038915-60-4  – CPF

    China Supplier Sugammadex Sodium - Niraparib 1038915-60-4 – CPF

    Description Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.   In Vitro Niraparib (MK-4827) inhibits PARP activity with EC50=4 nM and EC90=45 nM in a whole cell assay. MK-4827 inhibits proliferation of cancer cells with mutant BRCA-1 and BRCA-2 with CC50 in the 10-100 nM range. MK-4827 displays exce...
  • 8 Year Exporter Canagliflozin And Metformin - Thalidomide  – CPF

    8 Year Exporter Canagliflozin And Metformin - Thalidomide – CPF

    Background Thalidomide was introduced as a sedative drug,immunomodulatory agent and also is investigated for treating symptoms of many cancers.Thalidomide inhibits an E3 ubiquitin ligase, which is a CRBN-DDB1-Cul4A complex. Description Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. In Vitro Tha...
  • 100% Original Rosuvastatin Calcium 20 Mg Tab - Venetoclax 1257044-40-8  – CPF

    100% Original Rosuvastatin Calcium 20 Mg Tab - Venetoclax 1257044-40-8 – CPF

    维奈妥拉 Venetoclax 1257044-40-8 In-House     VCL-6A 98549-88-3 In-House     VCL-7A 1235865-75-4 In-House     VCLM2 1228780-72-0 In-House     VCLM2-2HCl 1628047-87-9 In-House     VCLM3 1228779-96-1 In-House Generic Name: venetoclax (ven ET oh klax) Brand Name: Venclexta, Venclexta Starting Pack Venetoclax is used to treat chronic lymphocytic leukemia or small lymphocytic leukemia in adults. Venetoclax is used alone or in combination with other cancer medicines to trea...
  • Popular Design for Doxycycline Hcl 100mg - Sacubitril Hemicalcium  – CPF

    Popular Design for Doxycycline Hcl 100mg - Sacubitril Hemicalcium – CPF

        沙库比曲半钙盐 Sacubitril Hemicalcium 1369773-39-6 In-House     沙库比曲钠盐 149690-05-1 In-House     LCZ-4 1426129-50-1 In-House     LCZ-7 1012341-48-8 In-House     LCZ-8 1012341-50-2 In-House     LCZ-9 149690-12-0 In-House   Background AHU-377 hemicalcium salt is a hemicalcium salt form of AHU-377. It is an inhibitor of neprilysin with IC50 value of 5 nM [1]. AHU-377 and the angiotensin II AT1 receptor antagonist valsartan compose LCZ696 in a 1:1 molar rati...
  • Hot sale Factory Doxycycline Hyclate 100mg For Bronchitis - Bictegravir 1611493-60-7  – CPF

    Hot sale Factory Doxycycline Hyclate 100mg For Bronchitis - Bictegravir 1611493-60-7 – CPF

    Description Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. In Vitro Bictegravir (BIC) inhibits the strand transfer activity with an IC50 of 7.5± 0.3 nM. Relative to its inhibition of strand transfer activity, Bictegravir is a much weaker inhibitor of 3′-processing activity of HIV-1 IN, with an IC50 of 241±51 nM. Bictegravir enhances the accumulation of 2-LTR circles ~5-fold relative to the mock-treated control and reduces the amount of authentic integrati...
  • OEM manufacturer Doxycycline Monohydrate For Pneumonia - Velpatasvir(PVP)  – CPF

    OEM manufacturer Doxycycline Monohydrate For Pneumonia - Velpatasvir(PVP) – CPF

    Foreign Names Velpatasvirum (Latin) Velpatasvir (German) Velpatasvir (French) Velpatasvir (Spanish) Generic Names Velpatasvir (OS: USAN) GS-5816 (IS) UNII-KCU0C7RS7Z (IS) Multi-ingredient medications containing velpatasvir:sofosbuvir/velpatasvir systemic Brand names: Epclusa Drug class(es): antiviral combinations Sofosbuvir/velpatasvir systemic is used in the treatment of:Hepatitis C sofosbuvir/velpatasvir/voxilaprevir systemic Brand names: Vosevi Drug class(es): antiviral combinations Sofosb...
  • 2020 Good Quality Canagliflozin Renal Dosing - Agomelatine  – CPF

    2020 Good Quality Canagliflozin Renal Dosing - Agomelatine – CPF

    Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu...
  • High Quality for Doxycycline Mono 100mg Capsule - Rosuvastatin Calcium  – CPF

    High Quality for Doxycycline Mono 100mg Capsule - Rosuvastatin Calcium – CPF

    瑞舒伐他汀钙 Rosuvastatin Calcium 147098-20-2 In-House/CEP     RSM(Crystal) 147118-40-9 In-House     RSM(Crude) 147118-40-9 In-House     RSP — In-House     RS-8 147118-36-3 In-House     RS-8-1 147118-37-4 In-House     TP-8 131466-61-0 In-House     TP-11 147118-35-2 In-House     TP-13 147118-39-6 In-House     RS-10 289042-12-2 In-House     RS-11 355806-00-7 In-House Description Rosuvastatin Calcium (BANM, JAN, USAN) is known as Rosuvastatin in the US. a...
  • Cheap PriceList for Doxycycline Mono 50 Mg - Chlorothiazide  – CPF

    Cheap PriceList for Doxycycline Mono 50 Mg - Chlorothiazide – CPF

    Background Chlorothiazide is an inhibitor of carbonic anhydrase and is slightly less potent than acetazolamide. This compound has been shown to block reabsorption of sodium and chloride ions. Description Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM) Target: Others Chlorothiazide sodium (Diuril) is a diuretic used within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. It is also used as an antihypertensive. Most often...
  • Fast delivery Telaprevir Dose - Sacubitril Hemicalcium  – CPF

    Fast delivery Telaprevir Dose - Sacubitril Hemicalcium – CPF

        沙库比曲半钙盐 Sacubitril Hemicalcium 1369773-39-6 In-House     沙库比曲钠盐 149690-05-1 In-House     LCZ-4 1426129-50-1 In-House     LCZ-7 1012341-48-8 In-House     LCZ-8 1012341-50-2 In-House     LCZ-9 149690-12-0 In-House   Background AHU-377 hemicalcium salt is a hemicalcium salt form of AHU-377. It is an inhibitor of neprilysin with IC50 value of 5 nM [1]. AHU-377 and the angiotensin II AT1 receptor antagonist valsartan compose LCZ696 in a 1:1 molar rati...
  • Hot New Products Doxycycline Hyclate 100mg Capsules Uses - Dabigatran Etexilate Mesylate  – CPF

    Hot New Products Doxycycline Hyclate 100mg Capsules Uses - Dabigatran Etexilate Mesylate – CPF

    Description Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active prodrug of Dabigatran. Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation. Background Description: IC50 Value: 4.5nM (Ki); 10nM(Thrombin-induced platelet aggregation) [1] Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) undergoing advanced clinical development as its orally active prodrug,dabiga...
  • High Quality for Doxycycline Hyclate 100mg Treats - Sacubitril Hemicalcium  – CPF

    High Quality for Doxycycline Hyclate 100mg Treats - Sacubitril Hemicalcium – CPF

        沙库比曲半钙盐 Sacubitril Hemicalcium 1369773-39-6 In-House     沙库比曲钠盐 149690-05-1 In-House     LCZ-4 1426129-50-1 In-House     LCZ-7 1012341-48-8 In-House     LCZ-8 1012341-50-2 In-House     LCZ-9 149690-12-0 In-House   Background AHU-377 hemicalcium salt is a hemicalcium salt form of AHU-377. It is an inhibitor of neprilysin with IC50 value of 5 nM [1]. AHU-377 and the angiotensin II AT1 receptor antagonist valsartan compose LCZ696 in a 1:1 molar rati...