1. As an adjunct to diet and exercise, to improve glycemic control in adults with type 2 diabetes mellitus.
2. As an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of ≥30 kg/m² (obesity) or ≥27 kg/m² (overweight) with at least one weight-related comorbidity.
3. For the treatment of moderate-to-severe obstructive sleep apnea (OSA) in adults with obesity.