Sugammadex Sodium

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  • Sugammadex Sodium

    Sugammadex Sodium

    API’s Name Indication Specification US DMF  EU DMF  CEP
    Sugammadex Sodium Neuromuscular blockade In-House      
  • China Factory for Ticagrelor Bnf - Enalapril Maleate  – CPF

    China Factory for Ticagrelor Bnf - Enalapril Maleate – CPF

    Background Enalapril Maleate Description Enalapril (maleate) (MK-421 (maleate)), the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor. In Vivo Enalapril (MK-421) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to enalaprilat following oral administration. Enalapril (MK-421) is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angio...
  • Cheap price Doxycycline Mono For Ear Infection - LOXO-101 1223403-58-4  – CPF

    Cheap price Doxycycline Mono For Ear Infection - LOXO-101 1223403-58-4 – CPF

    Background IC50: low nanomolar range for inhibition of all TRK family members LOXO-101 is a tropomyosin receptor kinases (TRK) inhibitor. The TRK family of neurotrophin receptors and their neurotrophin ligands regulate neuron growth, differentiation and survival. In vitro: In previous study, LOXO-101 was evaluated for off-target kinase enzyme inhibition against a panel of non-TRK kinases at a concentration of 1,000 nM and ATP concentrations around the Km. Results showed that LOXO-101 had grea...
  • Manufacturing Companies for Ticagrelor Cost - Bictegravir 1611493-60-7  – CPF

    Manufacturing Companies for Ticagrelor Cost - Bictegravir 1611493-60-7 – CPF

    Description Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. In Vitro Bictegravir (BIC) inhibits the strand transfer activity with an IC50 of 7.5± 0.3 nM. Relative to its inhibition of strand transfer activity, Bictegravir is a much weaker inhibitor of 3′-processing activity of HIV-1 IN, with an IC50 of 241±51 nM. Bictegravir enhances the accumulation of 2-LTR circles ~5-fold relative to the mock-treated control and reduces the amount of authentic integrati...
  • OEM Factory for Daclatasvir Manufacturer - Pregabalin  – CPF

    OEM Factory for Daclatasvir Manufacturer - Pregabalin – CPF

    Pregabalin is not a GABAA or GABAB receptor agonist. Pregabalin is a gabapentinoid and acts by inhibiting certain calcium channels. Specifically it is a ligand of the auxiliary α2δ subunit site of certain voltage-dependent calcium channels (VDCCs), and thereby acts as an inhibitor of α2δ subunit-containing VDCCs. There are two drug-binding α2δ subunits, α2δ-1 and α2δ-2, and pregabalin shows similar affinity for (and hence lack of selectivity between) these two sites. Pregabalin is selective i...
  • OEM/ODM Supplier Baloxavir Manufacturer - Thalidomide  – CPF

    OEM/ODM Supplier Baloxavir Manufacturer - Thalidomide – CPF

    Background Thalidomide was introduced as a sedative drug,immunomodulatory agent and also is investigated for treating symptoms of many cancers.Thalidomide inhibits an E3 ubiquitin ligase, which is a CRBN-DDB1-Cul4A complex. Description Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. In Vitro Tha...
  • Factory Supply Interdoxin 100 Doxycycline Hyclate - Apixaban  – CPF

    Factory Supply Interdoxin 100 Doxycycline Hyclate - Apixaban – CPF

    Background Apixaban is a highly selective and reversible inhibitor of Factor Xa with Ki values of 0.08 nM and 0.17 nM in human and rabbit, respectively[1]. Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade. Factor X is activated, by hydrolysis, into factor Xa by both factor IX. Factor Xa is the activated form of the coagulation factorthrombokinase.Inhibiting Factor Xa could offer an alternate method for anticoagulation. Direct Xa inhibitors are p...
  • Hot sale Doxycycline Monohydrate 50 Mg Capsule - Tofacitnib Citrate  – CPF

    Hot sale Doxycycline Monohydrate 50 Mg Capsule - Tofacitnib Citrate – CPF

    Background Tofacitinib citrate, also known as CP-690550 citrate, is a potent inhibitor of janus kinase 3 (JAK3), a hematopoetic cell-restricted tyrosine kinase involved in signal transduction regulating lymphocyte survival, proliferation, differentiation, and apoptosis.  The inhibition is JAK3 specific with a selectivity 1000-fold more than other non-JAK family kinases. Besides inhibiting JAKS (IC50 = 1 nM), tofacitinib citrate also inhibits janus kinase 2 (JAK2) and janus kinase 1 (JAK1) wit...
  • China Wholesale Rosuvastatin Calcium 5 Mg Tab Factory - Ticagrelor  – CPF

    China Wholesale Rosuvastatin Calcium 5 Mg Tab Factory - Ticagrelor – CPF

    Background Ticagrelor is a novel antagonist of the P2Y12 receptor [1]. Ticagrelor has been reported to inhibit the prothrombotic effects of ADP on the platelet by against the P2Y12 receptor. Ticagrelor has shown the complete inhibition of platelet aggregation ex vivo. In addition Ticagrelor has suggested a dose-dependent inhibition of platelet aggregation in human being. Apart from these, Ticagrelor has also demonstrated an orally, actively, reversibly binding antagonist. Unlike other inhibit...
  • Low price for Grateziano Sofosbuvir 400 Mg - Canagliflozin  – CPF

    Low price for Grateziano Sofosbuvir 400 Mg - Canagliflozin – CPF

    Background Canagliflozin is a novel, potent, and highly selective sodium glucose co-transporter (SGLT) 2 inhibitor [1]. It has been proved that Canagliflozin can increase urine glucose excretion by reducing the renal glucose threshold and by decreasing the filtered glucose re-absorption [2]. Canagliflozin has been shown to inhibit the Na+-mediated 14C-AMG intakes in CHO-hSGLT2, CHO-rat SGLT2 and CHO-mouse SGLT2 with IC50 values of 4.4, 3.7 and 2.0 nM, respectively [1]. Canagliflozin has been ...
  • China Wholesale Ticagrelor Uses Factory - Sofosbuvir  – CPF

    China Wholesale Ticagrelor Uses Factory - Sofosbuvir – CPF

    索非布韦 Sofosbuvir 1190307-88-0 In-House     SFBM 1256490-31-9 In-House     SFB-8 874638-80-9 In-House     SFB-10 817204-32-3 In-House     SFBA-1 863329-66-2 In-House     SFBMA 1334513-02-8 In-House Generic Name: sofosbuvir (soe FOS bue vir) Brand Names: Sovaldi Sofosbuvir is an antiviral medicine that is used to treat chronic hepatitis C in adults and children who are at least 3 years old and an HCV RNA replication inhibitor with an EC50 of 92 nM. Sofosbuvir must be...
  • Wholesale Price Tab Canagliflozin - Bictegravir 1611493-60-7  – CPF

    Wholesale Price Tab Canagliflozin - Bictegravir 1611493-60-7 – CPF

    Description Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. In Vitro Bictegravir (BIC) inhibits the strand transfer activity with an IC50 of 7.5± 0.3 nM. Relative to its inhibition of strand transfer activity, Bictegravir is a much weaker inhibitor of 3′-processing activity of HIV-1 IN, with an IC50 of 241±51 nM. Bictegravir enhances the accumulation of 2-LTR circles ~5-fold relative to the mock-treated control and reduces the amount of authentic integrati...