China China Wholesale Auro Rosuvastatin Calcium Manufacturers - Pitavastatin Calcium – CPF manufacturers and suppliers

China Wholesale Auro Rosuvastatin Calcium Manufacturers - Pitavastatin Calcium – CPF

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We have now our possess revenue group, design staff, technical crew, QC team and package group. We now have strict excellent regulate procedures for each process. Also, all of our workers are experienced in printing subject for Thalidomide Leprosy, Ticagrelor Clopidogrel, Baloxavir Marboxil For Uncomplicated Influenza, Welcome friends from all over the world come to visit, guide and negotiate.

China Wholesale Auro Rosuvastatin Calcium Manufacturers - Pitavastatin Calcium – CPF Detail:

匹伐他汀钙	Pitavastatin	147526-32-7	In-House
PI-5		3800-06-4	In-House
PI-6		145516-11-4	In-House
PI-7		121660-11-5	In-House

Description

Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity.

Background

Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Chemical structure

Pitavastatin Calcium

Related Biological Data

Pitavastatin Calcium2

2018 GMP-2
原料药GMP证书201811（captopril ,thalidomide etc）
GMP-of-PMDA-in-Chanyoo-平成28年08月03日　Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

OUR STRENGTH

Quality management1

Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.

Quality management2

Advanced international quality management system has laid solid foundation for sales.

Quality management3

Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.

Quality management4

Professional Regulatory Affairs team supports the quality demands during the application and registration.

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International cooperation

Domestic cooperation

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With responsible good quality method, good status and excellent client services, the series of solutions produced by our company are exported to lots of countries and regions for China Wholesale Auro Rosuvastatin Calcium Manufacturers - Pitavastatin Calcium – CPF , The product will supply to all over the world, such as: South Korea, Lebanon, Madras, Good quality and reasonable price have brought us stable customers and high reputation. Providing 'Quality Products, Excellent Service, Competitive Prices and Prompt Delivery', we are now looking forward to even greater cooperation with overseas customers based on mutual benefits. We will work whole-heartedly to improve our products and services. We also promise to work jointly with business partners to elevate our cooperation to a higher level and share success together. Warmly welcome you to visit our factory sincerely.

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