China China Wholesale Rosuvastatin Calcium 10 Suppliers - Agomelatine – CPF manufacturers and suppliers

China Wholesale Rosuvastatin Calcium 10 Suppliers - Agomelatine – CPF

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With state-of-the-art technologies and facilities, strict good quality regulate, reasonable cost, exceptional assistance and close co-operation with prospects, we're devoted to supplying the top benefit for our customers for Pregabalin And Nortriptyline Tablets, Pregabalin Indication, Rosuvastatin Calcium En Español, Our tenet is clear all the time: to deliver high quality product at competitive price to customers around the world. We welcome potential buyers to contact us for OEM and ODM orders.

China Wholesale Rosuvastatin Calcium 10 Suppliers - Agomelatine – CPF Detail:

Background

Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1].

Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned human MT1 and MT2 with Ki values of 0.09nM and 0.263nM, respectively. In the in vivo studies, agomelatine causes increase of dopamine and noradrenaline levels via blocking the inhibitory input of 5-HT2C. Moreover, the administration of agomelatine counteractes the stress-induced decrease in sucrose consumption in a rat model of depression. Besides that, agomelatine exerts alleviated anxiety efficacy in a rodent model of anxiety [1].

References:
[1] Zupancic M, Guilleminault C. Agomelatine. CNS drugs, 2006, 20(12): 981-992.

Chemical structure

Agomelatine

2018 GMP-2
原料药GMP证书201811（captopril ,thalidomide etc）
GMP-of-PMDA-in-Chanyoo-平成28年08月03日　Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

OUR STRENGTH

Quality management1

Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.

Quality management2

Advanced international quality management system has laid solid foundation for sales.

Quality management3

Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.

Quality management4

Professional Regulatory Affairs team supports the quality demands during the application and registration.

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To become the stage of realizing dreams of our employees! To build a happier, more united and extra professional workforce! To reach a mutual advantage of our prospects, suppliers, the society and ourselves for China Wholesale Rosuvastatin Calcium 10 Suppliers - Agomelatine – CPF , The product will supply to all over the world, such as: Oslo, New York, Malawi, Our company insists on the purpose of "takes service priority for standard, quality guarantee for the brand, do business in good faith, to offer skilled, rapid, accurate and timely service for you". We welcome old and new customers to negotiate with us. We are going to serve you with all sincerity!

Canagliflozin Prescribing Information

Celecoxib

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