China factory Outlets for Doxycycline Hyclate 50 Mg Acne - Canagliflozin – CPF manufacturers and suppliers

factory Outlets for Doxycycline Hyclate 50 Mg Acne - Canagliflozin – CPF

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Always customer-oriented, and it's our ultimate target to be not only the most reliable, trustable and honest supplier, but also the partner for our customers for Doxycycline Hyclate Monohydrate, Sofosbuvir, Doxycycline Hyclate, Our firm is dedicated to giving shoppers with significant and steady high quality goods at aggressive price tag, generating every single customer satisfied with our products and services.

factory Outlets for Doxycycline Hyclate 50 Mg Acne - Canagliflozin – CPF Detail:

Background

Canagliflozin is a novel, potent, and highly selective sodium glucose co-transporter (SGLT) 2 inhibitor [1]. It has been proved that Canagliflozin can increase urine glucose excretion by reducing the renal glucose threshold and by decreasing the filtered glucose re-absorption [2].

Canagliflozin has been shown to inhibit the Na+-mediated 14C-AMG intakes in CHO-hSGLT2, CHO-rat SGLT2 and CHO-mouse SGLT2 with IC50 values of 4.4, 3.7 and 2.0 nM, respectively [1].

Canagliflozin has been reported to reduce the blood glucose (BG) levels dose-dependently in both db/db Mice and Zucker diabetic fatty (ZDF) Rats. Additionally, canagliflozin has proved to decrease the respiratory exchange ratio, and body weight in DIO mice and ZDF rats [1].

Canagliflozin can be taken orally [1].

References:
[1] Liang Y1, Arakawa K, Ueta K, Matsushita Y, Kuriyama C Martin T, Du F, Liu Y, Xu J, Conway B, Conway J, Polidori D, Ways K, Demarest K. Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models. PLoS One. 2012;7(2):e30555
[2] Sarnoski-Brocavich S, Hilas O. Canagliflozin (Invokana), a Novel Oral Agent For Type-2 Diabetes. P T. 2013 Nov;38(11):656-66

Product Citation

Bahia Abbas Moussa, Marianne Alphonse Mahrouse, et al. “Different resolution techniques for management of overlapped spectra: Application for the determination of novel co-formulated hypoglycemic drugs in their combined pharmaceutical dosage form.” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Available online 20 June 2018.

Chemical structure

Canagliflozin

2018 GMP-2
原料药GMP证书201811（captopril ,thalidomide etc）
GMP-of-PMDA-in-Chanyoo-平成28年08月03日　Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

OUR STRENGTH

Quality management1

Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.

Quality management2

Advanced international quality management system has laid solid foundation for sales.

Quality management3

Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.

Quality management4

Professional Regulatory Affairs team supports the quality demands during the application and registration.

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Persisting in "High good quality, Prompt Delivery, Aggressive Price", we've established long-term cooperation with shoppers from each overseas and domestically and get new and previous clients' high comments for factory Outlets for Doxycycline Hyclate 50 Mg Acne - Canagliflozin – CPF , The product will supply to all over the world, such as: Monaco, Boston, Slovenia, All these products are manufactured in our factory located in China. So we can guarantee our quality seriously and availably. Within these four years we sell not only our products but also our service to clients throughout the world.

Problems can be quickly and effectively resolved, it is worth to be trust and working together.