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factory low price Agomelatine Supplier - Baloxavir Marboxil 1985606-14-1 – CPF
Background Baloxavir marboxil is an antiviral drug and is an endonuclease inhibitor. In rats and monkeys, the blood concentration of the drug is lower than the minimum detection amount in a single oral administration of the drug. In preclinical influenza A and B infection models (including strains that are resistant to existing antiviral drugs), Baloxavir marboxil has a certain effect. Chemical Properties Storage Store at -20°C M.Wt 571.55 Cas No. 1985606-14-1 Formula C27H23F2N3O7S ... -
2020 China New Design Doxycycline Hyclate 100mg For Bv - Niraparib 1038915-60-4 – CPF
Description Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity. In Vitro Niraparib (MK-4827) inhibits PARP activity with EC50=4 nM and EC90=45 nM in a whole cell assay. MK-4827 inhibits proliferation of cancer cells with mutant BRCA-1 and BRCA-2 with CC50 in the 10-100 nM range. MK-4827 displays exce... -
Factory Outlets Doxycycline Hyclate 100mg Cost - Ezetimibe – CPF
Background Ezetimibe is a potent and novel inhibitor of cholesterol absorption [1]. Cholesterol is a lipid molecule and is required to build and maintain membranes structural integrity and fluidity. Also, it serves as a precursor of vitamin D, bile acids and steroid hormones. In differentiated Caco-2 cells incubated with a carotenoid (1 μM), ezetimibe (10 mg/L) inhibited carotenoid transport with 50% inhibition for ɑ-carotene and β-carotene. Also, it inhibited the transport of β-cryptoxanthin... -
Reasonable price Ic Hydrochlorothiazide - Canagliflozin – CPF
Background Canagliflozin is a novel, potent, and highly selective sodium glucose co-transporter (SGLT) 2 inhibitor [1]. It has been proved that Canagliflozin can increase urine glucose excretion by reducing the renal glucose threshold and by decreasing the filtered glucose re-absorption [2]. Canagliflozin has been shown to inhibit the Na+-mediated 14C-AMG intakes in CHO-hSGLT2, CHO-rat SGLT2 and CHO-mouse SGLT2 with IC50 values of 4.4, 3.7 and 2.0 nM, respectively [1]. Canagliflozin has been ... -
Cheapest Price Monodox Doxycycline Monohydrate 100mg - Bictegravir 1611493-60-7 – CPF
Description Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. In Vitro Bictegravir (BIC) inhibits the strand transfer activity with an IC50 of 7.5± 0.3 nM. Relative to its inhibition of strand transfer activity, Bictegravir is a much weaker inhibitor of 3′-processing activity of HIV-1 IN, with an IC50 of 241±51 nM. Bictegravir enhances the accumulation of 2-LTR circles ~5-fold relative to the mock-treated control and reduces the amount of authentic integrati... -
Hot New Products Lcz696 Manufacturer - Sacubitril Hemicalcium – CPF
沙库比曲半钙盐 Sacubitril Hemicalcium 1369773-39-6 In-House 沙库比曲钠盐 149690-05-1 In-House LCZ-4 1426129-50-1 In-House LCZ-7 1012341-48-8 In-House LCZ-8 1012341-50-2 In-House LCZ-9 149690-12-0 In-House Background AHU-377 hemicalcium salt is a hemicalcium salt form of AHU-377. It is an inhibitor of neprilysin with IC50 value of 5 nM [1]. AHU-377 and the angiotensin II AT1 receptor antagonist valsartan compose LCZ696 in a 1:1 molar rati... -
Cheapest Factory Doxycycline Hyclate 100mg Uses - Enalapril Maleate – CPF
Background Enalapril Maleate Description Enalapril (maleate) (MK-421 (maleate)), the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor. In Vivo Enalapril (MK-421) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to enalaprilat following oral administration. Enalapril (MK-421) is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angio... -
Factory Free sample Venetoclax Manufacturer - Baloxavir Marboxil 1985606-14-1 – CPF
Background Baloxavir marboxil is an antiviral drug and is an endonuclease inhibitor. In rats and monkeys, the blood concentration of the drug is lower than the minimum detection amount in a single oral administration of the drug. In preclinical influenza A and B infection models (including strains that are resistant to existing antiviral drugs), Baloxavir marboxil has a certain effect. Chemical Properties Storage Store at -20°C M.Wt 571.55 Cas No. 1985606-14-1 Formula C27H23F2N3O7S ... -
China Wholesale Sliding Log Splitter Quotes – Hydrochlorothiazide – CPF
Description Hydrochlorothiazide (HCTZ), an orally active diuretic drug of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect. Background Hydrochlorothiazide is a diuretic drug of the thiazide class. In Vitro Hydrochlorothiazide belongs to thiazide class of di... -
Special Design for Agomelatine Manufacturer - Venetoclax 1257044-40-8 – CPF
维奈妥拉 Venetoclax 1257044-40-8 In-House VCL-6A 98549-88-3 In-House VCL-7A 1235865-75-4 In-House VCLM2 1228780-72-0 In-House VCLM2-2HCl 1628047-87-9 In-House VCLM3 1228779-96-1 In-House Generic Name: venetoclax (ven ET oh klax) Brand Name: Venclexta, Venclexta Starting Pack Venetoclax is used to treat chronic lymphocytic leukemia or small lymphocytic leukemia in adults. Venetoclax is used alone or in combination with other cancer medicines to tr... -
Factory wholesale Apixaban - Rivaroxaban – CPF
Background Rivaroxaban, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide, is a potent small-molecule inhibitor of factor Xa which is a coagulation factor at a critical juncture in the blood coagulation pathway resulting in the generation of thrombin and the formation of clot. Rivaroxaban binds to the Tyr288 in S1 pocket of factor Xa through the interaction of Tyr288 and the chlorine substituent of the chlorothiophene moiety. The inhi... -
China Wholesale Rosuvastatin Calcium 5 Mg Tab Tablet Quotes - Sofosbuvir – CPF
索非布韦 Sofosbuvir 1190307-88-0 In-House SFBM 1256490-31-9 In-House SFB-8 874638-80-9 In-House SFB-10 817204-32-3 In-House SFBA-1 863329-66-2 In-House SFBMA 1334513-02-8 In-House Generic Name: sofosbuvir (soe FOS bue vir) Brand Names: Sovaldi Sofosbuvir is an antiviral medicine that is used to treat chronic hepatitis C in adults and children who are at least 3 years old and an HCV RNA replication inhibitor with an EC50 of 92 nM. Sofosbuvir must ...
