Hydrochlorothiazide Mg

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  • Reliable Supplier Doxycycline Monohydrate Tablet - Thalidomide  – CPF

    Reliable Supplier Doxycycline Monohydrate Tablet - Thalidomide – CPF

    Background Thalidomide was introduced as a sedative drug,immunomodulatory agent and also is investigated for treating symptoms of many cancers.Thalidomide inhibits an E3 ubiquitin ligase, which is a CRBN-DDB1-Cul4A complex. Description Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. In Vitro Tha...
  • 100% Original History Of Thalidomide - Sugammadex Sodium  – CPF

    100% Original History Of Thalidomide - Sugammadex Sodium – CPF

    舒更葡糖钠 Sugammadex Sodium 343306-79-6 In-House Description Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a new reversal agent for neuromuscular block. Generic Name: sugammadex (soo GAM ma dex) Brand Name: Bridion Sugammadex reverses the effects of certain medications that are given during surgical procedures to relax your muscles. Sugammadex is used at the end of surgery, to help restore muscle function that has been blocked during surgery by the othe...
  • Factory making Sofosbuvir Dosage - Folic Acid  – CPF

    Factory making Sofosbuvir Dosage - Folic Acid – CPF

    Background Extracted from Spinacia oleracea;Store the product in sealed, cool and dry condition Description Folic acid(Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. Clinical Trial NCT Number Sponsor Condition Start Date Phase NCT03332602 Swiss Federal Institute of Technology Iron-deficiency April 4, 2018 Not Applicable Storage 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, ...
  • Reasonable price Rosuvastatin Calcium 40 Mg Tablet - LCZ696(Sacubitril + Valsartan)  – CPF

    Reasonable price Rosuvastatin Calcium 40 Mg Tablet - LCZ696(Sacubitril + Valsartan) – CPF

    Description LCZ696 (Sacubitril/Valsartan), comprised Valsartan (an ARB) and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure[1][2][3]. LCZ696 ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis.   Background LCZ696 is a first in class ARNi (angiotensin receptor neprilysin inhibitor) comprising anionic moieties of AR...
  • Ordinary Discount Doxycycline Hyclate 100mg Bronchitis - Rivaroxaban  – CPF

    Ordinary Discount Doxycycline Hyclate 100mg Bronchitis - Rivaroxaban – CPF

    Background Rivaroxaban, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide, is a potent small-molecule inhibitor of factor Xa which is a coagulation factor at a critical juncture in the blood coagulation pathway resulting in the generation of thrombin and the formation of clot. Rivaroxaban binds to the Tyr288 in S1 pocket of factor Xa through the interaction of Tyr288 and the chlorine substituent of the chlorothiophene moiety. The inhi...
  • Excellent quality Use Of Rosuvastatin Calcium - Doxycycline Hyclate  – CPF

    Excellent quality Use Of Rosuvastatin Calcium - Doxycycline Hyclate – CPF

    Background Doxycycline hyclate is an antibiotic [1]. Doxycycline hyclate is a derivative of tetracycline and possesses the activities of anti-inflammatory and antimicrobial. Doxycycline inhibits dengue virus replication in vitro with a temperature-dependent manner. The IC50 value is 52.3μM at 37°C and 26.7μM at 40°C. It inhibits the dengue virus via inhibiting the NS2B-NS3 serine protease of the virus. 60μM doxycycline reduces the CPE of the DNEV2-infected cells [1]. Doxycycline is found to b...
  • New Delivery for Remdesivir - Chlorothiazide  – CPF

    New Delivery for Remdesivir - Chlorothiazide – CPF

    Background Chlorothiazide is an inhibitor of carbonic anhydrase and is slightly less potent than acetazolamide. This compound has been shown to block reabsorption of sodium and chloride ions. Description Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM) Target: Others Chlorothiazide sodium (Diuril) is a diuretic used within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. It is also used as an antihypertensive. Most often...
  • 100% Original Factory Sglt2 Inhibitor Canagliflozin - Pregabalin  – CPF

    100% Original Factory Sglt2 Inhibitor Canagliflozin - Pregabalin – CPF

    Pregabalin is not a GABAA or GABAB receptor agonist. Pregabalin is a gabapentinoid and acts by inhibiting certain calcium channels. Specifically it is a ligand of the auxiliary α2δ subunit site of certain voltage-dependent calcium channels (VDCCs), and thereby acts as an inhibitor of α2δ subunit-containing VDCCs. There are two drug-binding α2δ subunits, α2δ-1 and α2δ-2, and pregabalin shows similar affinity for (and hence lack of selectivity between) these two sites. Pregabalin is selective i...
  • Europe style for Doxycycline Hyclate 50 Mg Cap - Pitavastatin Calcium  – CPF

    Europe style for Doxycycline Hyclate 50 Mg Cap - Pitavastatin Calcium – CPF

    匹伐他汀钙 Pitavastatin 147526-32-7 In-House     PI-5 3800-06-4 In-House     PI-6 145516-11-4 In-House     PI-7 121660-11-5 In-House   Description Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (L...
  • China Factory for Daclatasvir Supplier - Ribociclib 1374639-75-4  – CPF

    China Factory for Daclatasvir Supplier - Ribociclib 1374639-75-4 – CPF

    Description Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.   In Vitro Treating a panel of 17 neuroblastoma cell lines with Ribociclib (LEE011) across a four-log dose range (10 to 10,000 nM). Treatment with Ribociclib significantly inhibits substrate adherent growth relative to the control in 12 of the 17 neuroblastoma cell lines examined (mean IC50=306±68 nM, con...
  • 2020 Latest Design Sofosbuvir 400 Mg Daclatasvir 60 Mg - Daclatasvir Dihydrochloride  – CPF

    2020 Latest Design Sofosbuvir 400 Mg Daclatasvir 60 Mg - Daclatasvir Dihydrochloride – CPF

    Description Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir dihydrochloride is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively. IC50 & Target EC50: 50 pM (HCV replicon genotype 1a), 9 pM (HCV replicon genotype 1b), 71 pM (HCV replicon genotype 2a), 146 pM (HCV replicon ...
  • Low price for Doxycycline Hyclate For Sinus - Agomelatine  – CPF

    Low price for Doxycycline Hyclate For Sinus - Agomelatine – CPF

    Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu...