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Popular Design for Doxycycline Hcl 100mg - Agomelatine – CPF

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  • Popular Design for Doxycycline Hcl 100mg - Agomelatine – CPF

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We attempt for excellence, support the customers", hopes to become the top cooperation team and dominator enterprise for staff, suppliers and shoppers, realizes worth share and continual marketing for Canagliflozin Ppt, Doxycycline Hyclate Tablets, Pitavastatin, Created products with brand value. We attend seriously to produce and behave with integrity, and by the favor of customers at home and abroad in the xxx industry.
Popular Design for Doxycycline Hcl 100mg - Agomelatine – CPF Detail:

Background

Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1].

Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned human MT1 and MT2 with Ki values of 0.09nM and 0.263nM, respectively. In the in vivo studies, agomelatine causes increase of dopamine and noradrenaline levels via blocking the inhibitory input of 5-HT2C. Moreover, the administration of agomelatine counteractes the stress-induced decrease in sucrose consumption in a rat model of depression. Besides that, agomelatine exerts alleviated anxiety efficacy in a rodent model of anxiety [1].

References:
[1] Zupancic M, Guilleminault C. Agomelatine. CNS drugs, 2006, 20(12): 981-992.

Chemical structure

Agomelatine

2018 GMP-2
原料药GMP证书201811（captopril ,thalidomide etc）
GMP-of-PMDA-in-Chanyoo-平成28年08月03日　Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

OUR STRENGTH

Quality management1

Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.

Quality management2

Advanced international quality management system has laid solid foundation for sales.

Quality management3

Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect. 

Quality management4

Professional Regulatory Affairs team supports the quality demands during the application and registration.


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The incredibly rich projects administration experiences and a person to 1 service model make the substantial importance of organization communication and our easy understanding of your expectations for Popular Design for Doxycycline Hcl 100mg - Agomelatine – CPF , The product will supply to all over the world, such as: Montpellier, Anguilla, Lisbon, We have a dedicated and aggressive sales team, and many branches, catering to our customers. We are looking for long-term business partnerships, and ensure our suppliers that they will definitely benefit in both short and long run.
    • We always believe that the details decides the company's product quality, in this respect, the company conform our requirements and the goods are meet our expectations.
    5 Stars By Jodie from Seychelles - 2017.11.20 15:58
    The factory technical staff not only have high level of technology, their English level is also very good, this is a great help to technology communication.
    5 Stars By Modesty from Malawi - 2017.04.28 15:45
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