Baloxavir Marboxil 1985606-14-1

Short Description:

API’s Name Indication Innovator Patent Expiry Date(The U.S)
Baloxavir Marboxil 1985606-14-1 Influenza Shionogi & Roche Sep.21,2031


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Background

Baloxavir marboxil is an antiviral drug and is an endonuclease inhibitor. In rats and monkeys, the blood concentration of the drug is lower than the minimum detection amount in a single oral administration of the drug. In preclinical influenza A and B infection models (including strains that are resistant to existing antiviral drugs), Baloxavir marboxil has a certain effect.

Chemical Properties

Storage Store at -20°C
M.Wt 571.55
Cas No. 1985606-14-1
Formula C27H23F2N3O7S
Synonyms S-033188
Solubility Soluble in DMSO
Chemical Name (((R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl)oxy)methyl methyl carbonate
SDF Download SDF
Canonical SMILES O=C1C=CN(N([C@]2(N(C3=O)CCOC2)[H])[C@H]4C5=CC=C(C(F)=C5CSC6=CC=CC=C46)F)C3=C1OCOC(OC)=O
Shipping Condition Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tips For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Chemical structure

Baloxavir-Marboxil-1985606-14-1

CERTIFICATE

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

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