Low price for Doxycycline Hyclate For Sinus - Bictegravir 1611493-60-7 – CPF
Low price for Doxycycline Hyclate For Sinus - Bictegravir 1611493-60-7 – CPF Detail:
Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.
Bictegravir (BIC) inhibits the strand transfer activity with an IC50 of 7.5± 0.3 nM. Relative to its inhibition of strand transfer activity, Bictegravir is a much weaker inhibitor of 3′-processing activity of HIV-1 IN, with an IC50 of 241±51 nM. Bictegravir enhances the accumulation of 2-LTR circles ~5-fold relative to the mock-treated control and reduces the amount of authentic integration products in infected cells by 100-fold. Bictegravir potently inhibits HIV-1 replication in both MT-2 and MT-4 cells with EC50s of 1.5 and 2.4 nM, respectively. Bictegravir exhibits potent antiviral effects in both primary CD4+ T lymphocytes and monocyte-derived macrophages, with EC50s of 1.5±0.3 nM and 6.6±4.1 nM, respectively, which are comparable to values obtained in T-cell lines.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
|NCT Number||Sponsor||Condition||Start Date||
|NCT03998176||University of Nebraska|Gilead Sciences||HIV-1-infection||October 9, 2019||
|NCT03789968||Thomas Jefferson University|University of Maryland, College Park|Indiana University Health|The Brooklyn Hospital Center|University of Illinois at Chicago|Nova Southeastern University|University of California, San Francisco||HIV+AIDS||September 1, 2019|
|NCT04249037||University of Colorado, Denver|Gilead Sciences||HIV+AIDS||March 1, 2020||
|NCT04132674||Vancouver Infectious Diseases Centre||Human Immunodeficiency Virus I Infection|Drug Use||November 26, 2018||
|NCT04054089||Cristina Mussini|University of Modena and Reggio Emilia||HIV Infections||September 2019||
|NCT04155554||Azienda Ospedaliera Universitaria Senese|Catholic University of the Sacred Heart|Ospedale Policlinico San Martino|Azienda Ospedaliera San Paolo|Ospedale Amedeo di Savoia||HIV-1-infection||January 29, 2020||
|NCT02275065||Gilead Sciences||HIV-1 Infection||October 2014||
|NCT03711253||University of Southern California||Acute HIV Infection||October 14, 2019||
|NCT02400307||Gilead Sciences||HIV||April 17, 2015||
|NCT03499483||Fenway Community Health||HIV Prevention||January 24, 2019||
|NCT03502005||Midland Research Group, Inc.|Gilead Sciences||Human Immunodeficiency Virus||March 1, 2018||
Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.
Advanced international quality management system has laid solid foundation for sales.
Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.
Professional Regulatory Affairs team supports the quality demands during the application and registration.
Product detail pictures:
Related Product Guide:
Quality comes first; service is foremost; business is cooperation" is our business philosophy which is constantly observed and pursued by our company for Low price for Doxycycline Hyclate For Sinus - Bictegravir 1611493-60-7 – CPF , The product will supply to all over the world, such as: Qatar, Indonesia, Cambodia, Regarding quality as survival, prestige as guarantee, innovation as motive force, development along with advanced technology, our group hopes to make progress together with you and make untiring efforts for the bright future of this industry.
By Joseph from Nairobi - 2018.11.02 11:11
We are old friends, the company's product quality has been always very good and this time the price is also very cheap.
By Marcy Real from Lyon - 2017.04.28 15:45