1. As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
2. For chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity.
3. To reduce the risk of major adverse cardiovascular events (MACE) in adults with type 2 diabetes mellitus and established cardiovascular disease.
4. To reduce the risk of sustained eGFR decline, end-stage kidney disease, and cardiovascular death in adults with type 2 diabetes mellitus and chronic kidney disease.
