Is Hydrochlorothiazide

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  • Reliable Supplier Doxycycline Hyclate For Cellulitis - Dabigatran Etexilate Mesylate  – CPF

    Reliable Supplier Doxycycline Hyclate For Cellulitis - Dabigatran Etexilate Mesylate – CPF

    Description Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active prodrug of Dabigatran. Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation. Background Description: IC50 Value: 4.5nM (Ki); 10nM(Thrombin-induced platelet aggregation) [1] Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) undergoing advanced clinical development as its orally active prodrug,dabiga...
  • China New Product Rosuvastatin Calcium Use - Thalidomide  – CPF

    China New Product Rosuvastatin Calcium Use - Thalidomide – CPF

    Background Thalidomide was introduced as a sedative drug,immunomodulatory agent and also is investigated for treating symptoms of many cancers.Thalidomide inhibits an E3 ubiquitin ligase, which is a CRBN-DDB1-Cul4A complex. Description Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. In Vitro Tha...
  • Cheap PriceList for Ezetimibe - Hydrochlorothiazide  – CPF

    Cheap PriceList for Ezetimibe - Hydrochlorothiazide – CPF

    Description Hydrochlorothiazide (HCTZ), an orally active diuretic drug of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect. Background Hydrochlorothiazide is a diuretic drug of the thiazide class. In Vitro Hydrochlorothiazide belongs to thiazide class of di...
  • China Wholesale Central Hydraulics Log Splitter Quotes - Captopril  – CPF

    China Wholesale Central Hydraulics Log Splitter Quotes - Captopril – CPF

    Description Captopril (SQ-14534) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE). In Vitro Captopril (SQ-14534) has been shown to have similar morbidity and mortality benefits to those of diuretics and beta-blockers in hypertensive patients. Captopril (SQ-14534) has been shown to delay the progression of diabetic nephropathy, and enalapril and lisinopril prevent the development of nephropathy in normoalbuminuric patients with diabetes[1]. An equimolar ratio of the c...
  • Factory making Sofosbuvir Dosage - Daclatasvir Dihydrochloride  – CPF

    Factory making Sofosbuvir Dosage - Daclatasvir Dihydrochloride – CPF

    Description Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir dihydrochloride is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively. IC50 & Target EC50: 50 pM (HCV replicon genotype 1a), 9 pM (HCV replicon genotype 1b), 71 pM (HCV replicon genotype 2a), 146 pM (HCV replicon ...
  • Trending Products Sacubitril Manufacturer - Sugammadex Sodium  – CPF

    Trending Products Sacubitril Manufacturer - Sugammadex Sodium – CPF

    舒更葡糖钠 Sugammadex Sodium 343306-79-6 In-House Description Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a new reversal agent for neuromuscular block. Generic Name: sugammadex (soo GAM ma dex) Brand Name: Bridion Sugammadex reverses the effects of certain medications that are given during surgical procedures to relax your muscles. Sugammadex is used at the end of surgery, to help restore muscle function that has been blocked during surgery by the other ...
  • Leading Manufacturer for Daclatasvir Prescribing Information - Tofacitnib Citrate  – CPF

    Leading Manufacturer for Daclatasvir Prescribing Information - Tofacitnib Citrate – CPF

    Background Tofacitinib citrate, also known as CP-690550 citrate, is a potent inhibitor of janus kinase 3 (JAK3), a hematopoetic cell-restricted tyrosine kinase involved in signal transduction regulating lymphocyte survival, proliferation, differentiation, and apoptosis.  The inhibition is JAK3 specific with a selectivity 1000-fold more than other non-JAK family kinases. Besides inhibiting JAKS (IC50 = 1 nM), tofacitinib citrate also inhibits janus kinase 2 (JAK2) and janus kinase 1 (JAK1) wit...
  • 8 Year Exporter Canagliflozin And Metformin - Sofosbuvir  – CPF

    8 Year Exporter Canagliflozin And Metformin - Sofosbuvir – CPF

    索非布韦 Sofosbuvir 1190307-88-0 In-House     SFBM 1256490-31-9 In-House     SFB-8 874638-80-9 In-House     SFB-10 817204-32-3 In-House     SFBA-1 863329-66-2 In-House     SFBMA 1334513-02-8 In-House Generic Name: sofosbuvir (soe FOS bue vir) Brand Names: Sovaldi Sofosbuvir is an antiviral medicine that is used to treat chronic hepatitis C in adults and children who are at least 3 years old and an HCV RNA replication inhibitor with an EC50 of 92 nM. Sofosbuvir must be...
  • Factory wholesale Doxycycline Hyclate For Chlamydia - Pregabalin  – CPF

    Factory wholesale Doxycycline Hyclate For Chlamydia - Pregabalin – CPF

    Pregabalin is not a GABAA or GABAB receptor agonist. Pregabalin is a gabapentinoid and acts by inhibiting certain calcium channels. Specifically it is a ligand of the auxiliary α2δ subunit site of certain voltage-dependent calcium channels (VDCCs), and thereby acts as an inhibitor of α2δ subunit-containing VDCCs. There are two drug-binding α2δ subunits, α2δ-1 and α2δ-2, and pregabalin shows similar affinity for (and hence lack of selectivity between) these two sites. Pregabalin is selective i...
  • Manufacturer of Obeticholic Acid Uses - Baloxavir Marboxil 1985606-14-1  – CPF

    Manufacturer of Obeticholic Acid Uses - Baloxavir Marboxil 1985606-14-1 – CPF

    Background Baloxavir marboxil is an antiviral drug and is an endonuclease inhibitor. In rats and monkeys, the blood concentration of the drug is lower than the minimum detection amount in a single oral administration of the drug. In preclinical influenza A and B infection models (including strains that are resistant to existing antiviral drugs), Baloxavir marboxil has a certain effect. Chemical Properties Storage Store at -20°C M.Wt 571.55 Cas No. 1985606-14-1 Formula C27H23F2N3O7S ...
  • Special Price for Daclatasvir Plus Sofosbuvir - Apixaban  – CPF

    Special Price for Daclatasvir Plus Sofosbuvir - Apixaban – CPF

    Background Apixaban is a highly selective and reversible inhibitor of Factor Xa with Ki values of 0.08 nM and 0.17 nM in human and rabbit, respectively[1]. Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade. Factor X is activated, by hydrolysis, into factor Xa by both factor IX. Factor Xa is the activated form of the coagulation factorthrombokinase.Inhibiting Factor Xa could offer an alternate method for anticoagulation. Direct Xa inhibitors are p...
  • China Wholesale Rosuvastatin Calcium Tablets 10mg Manufacturers - Pitavastatin Calcium  – CPF

    China Wholesale Rosuvastatin Calcium Tablets 10mg Manufacturers - Pitavastatin Calcium – CPF

    匹伐他汀钙 Pitavastatin 147526-32-7 In-House     PI-5 3800-06-4 In-House     PI-6 145516-11-4 In-House     PI-7 121660-11-5 In-House   Description Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (L...